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VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20261001T003744Z
UID:https://www.mpgc-mainz.de/events/32593/2368
DTSTART;VALUE=DATE:20230208
DTEND;VALUE=DATE:20230209
CLASS:PUBLIC
CREATED:20221018T121328Z
DESCRIPTION:Supramolecular assemblies in nature are the embodiment of creat
 ing function through structure formation. In recent years\, these complex 
 natural architectures have inspired the development of materials for the i
 n-situ formation of synthetic nanostructures inside living cells. Syntheti
 c intracellular assemblies can be used to modulate cellular processes\, ho
 wever\, their effects on metabolism and three-dimensional cell networks ha
 ve not been widely explored. Herein\, we present bioresponsive kinked pept
 ides that can undergo a multistep transformation into self-assembling line
 ar peptides in living cells. The intracellular peptide assembly causes met
 abolic disruption and rapid cell death. This work showcases the potential 
 use of bioresponsive nanomaterials as supramolecular anticancer drugs via 
 the construction of synthetic architectures inside living cells.\nSpeaker:
  Sarah Chagri
LAST-MODIFIED:20221104T122714Z
LOCATION:
SUMMARY:Synthetic Structure Formation in Living Cells via Stimulus-Responsi
 ve Peptide Assembly
URL;VALUE=URI:https://www.mpgc-mainz.de/events/32593/2368
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