Designing bioresponsive nanomaterials for intracellular self-assembly

Imitating nature's supramolecular assemblies inside cells is a challenging task that could help advance nanomedicine and synthetic biology. This review highlights recent advances in the design of synthetic materials for intracellular self-assembly.

May 18, 2022

Supramolecular assemblies are abundant in nature. These dynamic nanostructures made of proteins, lipids or oligonucleotides fulfill many biological purposes within a cellular environment and serve as inspiration for synthetic materials designed for intracellular self-assembly. This review highlights recent progress in the development of bioresponsive nanomaterials capable of exploiting biological triggers to form complex functional architectures inside living cells.

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