Anne Huppertsberg: Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Immune Modulators
- Date: May 12, 2021
- Speaker: Anne Huppertsberg
In this presentation, I will report on a novel nanogel platform based on polymerizable squaric ester amides for a more robust and hydrolysis-resistant post-polymerization modification of pH-degradable, immunodrug-loaded nanogels. Further, the nanocarrier's blood stability, biodistribution and potential protein corona are characterized showing that this nanocarrier can permit safe intravenous administation of immune modulators.